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Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling
Many pathogenic bacteria cause local infections but occasionally invade into the blood stream, often with fatal outcome. Very little is known about the mechanism underlying the switch from local to invasive infection. In the case of Neisseria gonorrhoeae, phase variable type 4 pili (T4P) stabilize l...
Autores principales: | Faulstich, Michaela, Böttcher, Jan-Peter, Meyer, Thomas F., Fraunholz, Martin, Rudel, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662692/ https://www.ncbi.nlm.nih.gov/pubmed/23717204 http://dx.doi.org/10.1371/journal.ppat.1003373 |
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