Simultaneous Identification of Multiple Driver Pathways in Cancer

Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identif...

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Detalles Bibliográficos
Autores principales: Leiserson, Mark D. M., Blokh, Dima, Sharan, Roded, Raphael, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662702/
https://www.ncbi.nlm.nih.gov/pubmed/23717195
http://dx.doi.org/10.1371/journal.pcbi.1003054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662702/
https://www.ncbi.nlm.nih.gov/pubmed/23717195
http://dx.doi.org/10.1371/journal.pcbi.1003054

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