Microbial Translocation Is Associated with Extensive Immune Activation in Dengue Virus Infected Patients with Severe Disease

BACKGROUND: Severe dengue virus (DENV) disease is associated with extensive immune activation, characterized by a cytokine storm. Previously, elevated lipopolysaccharide (LPS) levels in dengue were found to correlate with clinical disease severity. In the present cross-sectional study we identified...

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Detalles Bibliográficos
Autores principales: van de Weg, Cornelia A. M., Pannuti, Cláudio S., de Araújo, Evaldo S. A., van den Ham, Henk-Jan, Andeweg, Arno C., Boas, Lucy S. V., Felix, Alvina C., Carvalho, Karina I., de Matos, Andreia M., Levi, José E., Romano, Camila M., Centrone, Cristiane C., de Lima Rodrigues, Celia L., Luna, Expedito, van Gorp, Eric C. M., Osterhaus, Albert D. M. E., Martina, Byron E. E., Kallas, Esper G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662706/
https://www.ncbi.nlm.nih.gov/pubmed/23717702
http://dx.doi.org/10.1371/journal.pntd.0002236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662706/
https://www.ncbi.nlm.nih.gov/pubmed/23717702
http://dx.doi.org/10.1371/journal.pntd.0002236

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