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Global Fit Analysis of Myosin-5b Motility Reveals Thermodynamics of Mg(2+)-Sensitive Acto-Myosin-ADP States

Kinetic and thermodynamic studies of the mechanochemical cycle of myosin motors are essential for understanding the mechanism of energy conversion. Here, we report our investigation of temperature and free Mg(2+)-ion dependencies of sliding velocities of a high duty ratio class-5 myosin motor, myosi...

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Detalles Bibliográficos
Autores principales: Chizhov, Igor, Hartmann, Falk K., Hundt, Nikolas, Tsiavaliaris, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662761/
https://www.ncbi.nlm.nih.gov/pubmed/23738001
http://dx.doi.org/10.1371/journal.pone.0064797