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Single Nucleotide Polymorphisms in the Tumor Necrosis Factor-Alpha Gene Promoter Region Alter the Risk of Psoriasis Vulgaris and Psoriatic Arthritis: A Meta-Analysis

BACKGROUND: It has been confirmed that tumor necrosis factor-alpha (TNFα), a macrophage-derived pro-inflammatory cytokine, plays an important role in the pathogenesis of psoriasis vulgaris and psoriatic arthritis (PsV&PsA). In contrast, the reported association of TNFα gene promoter region singl...

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Detalles Bibliográficos
Autores principales: Zhu, Junqing, Qu, Hongda, Chen, Xiaoguang, Wang, Hao, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662764/
https://www.ncbi.nlm.nih.gov/pubmed/23717605
http://dx.doi.org/10.1371/journal.pone.0064376