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How Ionic Strength Affects the Conformational Behavior of Human and Rat Beta Amyloids – A Computational Study
Progressive cerebral deposition of amyloid beta occurs in Alzheimeŕs disease and during the aging of certain mammals (human, monkey, dog, bear, cow, cat) but not others (rat, mouse). It is possibly due to different amino acid sequences at positions 5, 10 and 13. To address this issue, we performed s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662769/ https://www.ncbi.nlm.nih.gov/pubmed/23717395 http://dx.doi.org/10.1371/journal.pone.0062914 |