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Genomic insights into cancer-associated aberrant CpG island hypermethylation
Carcinogenesis is thought to occur through a combination of mutational and epimutational events that disrupt key pathways regulating cellular growth and division. The DNA methylomes of cancer cells can exhibit two striking differences from normal cells; a global reduction of DNA methylation levels a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662888/ https://www.ncbi.nlm.nih.gov/pubmed/23341493 http://dx.doi.org/10.1093/bfgp/els063 |