Calculation of substrate binding affinities for a bacterial GH78 rhamnosidase through molecular dynamics simulations

Ram2 from Pediococcus acidilactici is a rhamnosidase from the glycoside hydrolase family 78. It shows remarkable selectivity for rutinose rather than para-nitrophenyl-alpha-l-rhamnopyranoside (p-NPR). Molecular dynamics simulations were performed using a homology model of this enzyme, in complex wit...

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Detalles Bibliográficos
Autores principales: Grandits, Melanie, Michlmayr, Herbert, Sygmund, Christoph, Oostenbrink, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663046/
https://www.ncbi.nlm.nih.gov/pubmed/23914137
http://dx.doi.org/10.1016/j.molcatb.2013.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663046/
https://www.ncbi.nlm.nih.gov/pubmed/23914137
http://dx.doi.org/10.1016/j.molcatb.2013.03.012

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