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Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells

BACKGROUND: The forkhead transcription factor FOXM1 is a key regulator of the cell cycle. It is frequently over-expressed in cancer and is emerging as an important therapeutic target. In breast cancer FOXM1 expression is linked with estrogen receptor (ERα) activity and resistance to endocrine therap...

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Detalles Bibliográficos
Autores principales: Sanders, Deborah A, Ross-Innes, Caryn S, Beraldi, Dario, Carroll, Jason S, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663086/
https://www.ncbi.nlm.nih.gov/pubmed/23347430
http://dx.doi.org/10.1186/gb-2013-14-1-r6