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EMu: probabilistic inference of mutational processes and their localization in the cancer genome
The spectrum of mutations discovered in cancer genomes can be explained by the activity of a few elementary mutational processes. We present a novel probabilistic method, EMu, to infer the mutational signatures of these processes from a collection of sequenced tumors. EMu naturally incorporates the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663107/ https://www.ncbi.nlm.nih.gov/pubmed/23628380 http://dx.doi.org/10.1186/gb-2013-14-4-r39 |