Cargando…

Inferring the kinetics of stochastic gene expression from single-cell RNA-sequencing data

BACKGROUND: Genetically identical populations of cells grown in the same environmental condition show substantial variability in gene expression profiles. Although single-cell RNA-seq provides an opportunity to explore this phenomenon, statistical methods need to be developed to interpret the variab...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jong Kyoung, Marioni, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663116/
https://www.ncbi.nlm.nih.gov/pubmed/23360624
http://dx.doi.org/10.1186/gb-2013-14-1-r7