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Inferring the kinetics of stochastic gene expression from single-cell RNA-sequencing data
BACKGROUND: Genetically identical populations of cells grown in the same environmental condition show substantial variability in gene expression profiles. Although single-cell RNA-seq provides an opportunity to explore this phenomenon, statistical methods need to be developed to interpret the variab...
Autores principales: | Kim, Jong Kyoung, Marioni, John C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663116/ https://www.ncbi.nlm.nih.gov/pubmed/23360624 http://dx.doi.org/10.1186/gb-2013-14-1-r7 |
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