Cargando…

Keto-Mycolic Acid-Dependent Pellicle Formation Confers Tolerance to Drug-Sensitive Mycobacterium tuberculosis

The chronic nature of tuberculosis (TB), its requirement of long duration of treatment, its ability to evade immune intervention, and its propensity to relapse after drug treatment is discontinued are reminiscent of other chronic, biofilm-associated bacterial diseases. Historically, Mycobacterium tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Sambandan, Dhinakaran, Dao, Dee N., Weinrick, Brian C., Vilchèze, Catherine, Gurcha, Sudagar S., Ojha, Anil, Kremer, Laurent, Besra, Gurdyal S., Hatfull, Graham F., Jacobs, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663190/
https://www.ncbi.nlm.nih.gov/pubmed/23653446
http://dx.doi.org/10.1128/mBio.00222-13