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New Conotoxin SO-3 Targeting N-type Voltage-Sensitive Calcium Channels

Selective blockers of the N-type voltage-sensitive calcium (Ca(V)) channels are useful in the management of severe chronic pain. Here, the structure and function characteristics of a novel N-type Ca(V) channel blocker, SO-3, are reviewed. SO-3 is a 25- amino acid conopeptide originally derived from...

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Detalles Bibliográficos
Autores principales: Wen, Lei, Yang, Sheng, Zhou, Wenxia, Zhang, Yongxiang, Huang, Peitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663411/