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Clinical Neuropathology Practice News 2-2013: immunohistochemistry pins IDH in glioma – molecular testing procedures under scrutiny

Isocitrate dehydrogenase 1 (IDH1) gene mutations occur in ~ 60 – 90% of diffuse and anaplastic gliomas and secondary glioblastomas. IDH status is strongly associated with patient survival times and IDH testing is relevant for clinical patient management and for stratification in clinical trials. A r...

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Detalles Bibliográficos
Autores principales: Preusser, Matthias, van den Bent, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663465/
https://www.ncbi.nlm.nih.gov/pubmed/23442355
http://dx.doi.org/10.5414/NP300622