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Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity

BACKGROUND: Co-Activator Arginine Methyltransferase 1(CARM1) is an Estrogen Receptor (ER) cofactor that remodels chromatin for gene regulation via methylation of Histone3. We investigated CARM1 levels and localization across breast cancer tumors in a cohort of patients of either European or African...

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Detalles Bibliográficos
Autores principales: Davis, Melissa B, Liu, Xinyu, Wang, Shiyao, Reeves, Jaxk, Khramtsov, Andrey, Huo, Dezheng, Olopade, Olufunmilayo I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663705/
https://www.ncbi.nlm.nih.gov/pubmed/23663560
http://dx.doi.org/10.1186/1476-4598-12-40