Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D

BACKGROUND: Stalled replication forks at common fragile sites are a major cause of genomic instability. RecQ helicases, a highly conserved family of DNA-unwinding enzymes, are believed to ease ‘roadblocks’ that pose challenge to replication fork progression. Among the five known RecQ homologs in hum...

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Detalles Bibliográficos
Autores principales: Lu, Xing, Parvathaneni, Swetha, Hara, Toshifumi, Lal, Ashish, Sharma, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663727/
https://www.ncbi.nlm.nih.gov/pubmed/23601052
http://dx.doi.org/10.1186/1476-4598-12-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663727/
https://www.ncbi.nlm.nih.gov/pubmed/23601052
http://dx.doi.org/10.1186/1476-4598-12-29

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