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Assessing the Amount of Quadruplex Structures Present within G(2)-Tract Synthetic Random-Sequence DNA Libraries

The process of in vitro selection has led to the discovery of many aptamers with potential to be developed into inhibitors and biosensors, but problems in isolating aptamers against certain targets with desired affinity and specificity still remain. One possible improvement is to use libraries enhan...

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Detalles Bibliográficos
Autores principales: McManus, Simon A., Li, Yingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663748/
https://www.ncbi.nlm.nih.gov/pubmed/23717551
http://dx.doi.org/10.1371/journal.pone.0064131