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Active subnetwork recovery with a mechanism-dependent scoring function; with application to angiogenesis and organogenesis studies

BACKGROUND: The learning active subnetworks problem involves finding subnetworks of a bio-molecular network that are active in a particular condition. Many approaches integrate observation data (e.g., gene expression) with the network topology to find candidate subnetworks. Increasingly, pathway dat...

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Detalles Bibliográficos
Autores principales: Lichtenstein, Ilana, Charleston, Michael A, Caetano, Tiberio S, Gamble, Jennifer R, Vadas, Mathew A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663784/
https://www.ncbi.nlm.nih.gov/pubmed/23432934
http://dx.doi.org/10.1186/1471-2105-14-59