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Active subnetwork recovery with a mechanism-dependent scoring function; with application to angiogenesis and organogenesis studies
BACKGROUND: The learning active subnetworks problem involves finding subnetworks of a bio-molecular network that are active in a particular condition. Many approaches integrate observation data (e.g., gene expression) with the network topology to find candidate subnetworks. Increasingly, pathway dat...
Autores principales: | Lichtenstein, Ilana, Charleston, Michael A, Caetano, Tiberio S, Gamble, Jennifer R, Vadas, Mathew A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663784/ https://www.ncbi.nlm.nih.gov/pubmed/23432934 http://dx.doi.org/10.1186/1471-2105-14-59 |
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