Interferon Regulatory Factor 8-Deficiency Determines Massive Neutrophil Recruitment but T Cell Defect in Fast Growing Granulomas during Tuberculosis

Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS). Interferon regulatory factor-8 (IRF-8) plays an important role in host defense against Mtb, al...

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Detalles Bibliográficos
Autores principales: Rocca, Stefano, Schiavoni, Giovanna, Sali, Michela, Anfossi, Antonio Giovanni, Abalsamo, Laura, Palucci, Ivana, Mattei, Fabrizio, Sanchez, Massimo, Giagu, Anna, Antuofermo, Elisabetta, Fadda, Giovanni, Belardelli, Filippo, Delogu, Giovanni, Gabriele, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663794/
https://www.ncbi.nlm.nih.gov/pubmed/23717393
http://dx.doi.org/10.1371/journal.pone.0062751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663794/
https://www.ncbi.nlm.nih.gov/pubmed/23717393
http://dx.doi.org/10.1371/journal.pone.0062751

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