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High Doses of Ursodeoxycholic Acid Up-Regulate the Expression of Placental Breast Cancer Resistance Protein in Patients Affected by Intrahepatic Cholestasis of Pregnancy

BACKGROUND: Ursodeoxycholic acid (UDCA) administration in intrahepatic cholestasis of pregnancy (ICP) induces bile acids (BA) efflux from the foetal compartment, but the molecular basis of this transplacental transport is only partially defined. AIM: To determine if placental breast cancer resistanc...

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Detalles Bibliográficos
Autores principales: Azzaroli, Francesco, Raspanti, Maria Elena, Simoni, Patrizia, Montagnani, Marco, Lisotti, Andrea, Cecinato, Paolo, Arena, Rosario, Simonazzi, Giuliana, Farina, Antonio, Rizzo, Nicola, Mazzella, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663799/
https://www.ncbi.nlm.nih.gov/pubmed/23717540
http://dx.doi.org/10.1371/journal.pone.0064101