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Bioequivalance and pharmacokinetic study of febuxostat in human plasma by using LC-MS/MS with liquid liquid extraction method

A bioequivalence study was proved of generic Febuxostat 80 mg tablets (T) in healthy volunteers.For this purpose, Authors developed a simple, sensitive, selective, rapid, rugged and reproducible liquid chromatography–tandem mass spectrometry method for the quantification of Febuxostat (FB) in human...

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Detalles Bibliográficos
Autores principales: Chandu, Babu Rao, Kanala, Kanchanamala, Hwisa, Nagiat T, Katakam, Prakash, Khagga, Mukkanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664180/
https://www.ncbi.nlm.nih.gov/pubmed/23741640
http://dx.doi.org/10.1186/2193-1801-2-194