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Bioavailability of intravenous fosphenytoin sodium in healthy Japanese volunteers

To compare and evaluate the bioavailability for intravenous fosphenytoin sodium with that of intravenous phenytoin sodium in Japanese subjects. In study 1, healthy Japanese male volunteers received a 30-min infusion of 375 mg fosphenytoin sodium or an equimolar dose of 250 mg phenytoin by a double-b...

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Detalles Bibliográficos
Autores principales: Inoue, Yushi, Usui, Naotaka, Hiroki, Tadayuki, Shimizu, Kenji, Kobayashi, Susumu, Shimasaki, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664181/
https://www.ncbi.nlm.nih.gov/pubmed/22968854
http://dx.doi.org/10.1007/s13318-012-0105-x