Cargando…

Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn

AT-rich interaction domain molecule 3B (ARID3B) and MYCN are expressed in a portion of neuroblastoma, and form a combination that has strong oncogenic activity in mouse embryonic fibroblasts (MEFs). Here, we show that this combination can also convert neural stem cells to neuroblastoma-like tumor. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, K, Jakt, L M, Nishikawa, S-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664305/
https://www.ncbi.nlm.nih.gov/pubmed/22751132
http://dx.doi.org/10.1038/onc.2012.285