Transcriptional Repression of Gata3 Is Essential for Early B Cell Commitment

The mechanisms underlying the silencing of alternative fate potentials in very early B cell precursors remain unclear. Using gain- and loss-of-function approaches together with a synthetic Zinc-finger polypeptide (6ZFP) engineered to prevent transcription factor binding to a defined cis element, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Anupam, Northrup, Daniel, Boukarabila, Hanane, Jacobsen, Sten Erik W., Allman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664383/
https://www.ncbi.nlm.nih.gov/pubmed/23684985
http://dx.doi.org/10.1016/j.immuni.2013.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664383/
https://www.ncbi.nlm.nih.gov/pubmed/23684985
http://dx.doi.org/10.1016/j.immuni.2013.01.014

Ejemplares similares