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Transcriptional Repression of Gata3 Is Essential for Early B Cell Commitment
The mechanisms underlying the silencing of alternative fate potentials in very early B cell precursors remain unclear. Using gain- and loss-of-function approaches together with a synthetic Zinc-finger polypeptide (6ZFP) engineered to prevent transcription factor binding to a defined cis element, we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664383/ https://www.ncbi.nlm.nih.gov/pubmed/23684985 http://dx.doi.org/10.1016/j.immuni.2013.01.014 |