Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump

The MtrCDE multidrug pump, from Neisseria gonorrhoeae, is assembled from the inner and outer membrane proteins MtrD and MtrE, which are connected by the periplasmic membrane fusion protein MtrC. Although it is clear that MtrD delivers drugs to the channel of MtrE, it remains unclear how drug deliver...

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Detalles Bibliográficos
Autores principales: Janganan, Thamarai K, Bavro, Vassiliy N, Zhang, Li, Borges-Walmsley, Maria Inês, Walmsley, Adrian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664412/
https://www.ncbi.nlm.nih.gov/pubmed/23565750
http://dx.doi.org/10.1111/mmi.12211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664412/
https://www.ncbi.nlm.nih.gov/pubmed/23565750
http://dx.doi.org/10.1111/mmi.12211

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