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Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump
The MtrCDE multidrug pump, from Neisseria gonorrhoeae, is assembled from the inner and outer membrane proteins MtrD and MtrE, which are connected by the periplasmic membrane fusion protein MtrC. Although it is clear that MtrD delivers drugs to the channel of MtrE, it remains unclear how drug deliver...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664412/ https://www.ncbi.nlm.nih.gov/pubmed/23565750 http://dx.doi.org/10.1111/mmi.12211 |