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VIPhyb, an Antagonist of Vasoactive Intestinal Peptide Receptor, Enhances Cellular Antiviral Immunity in Murine Cytomegalovirus Infected Mice

Vasoactive intestinal peptide (VIP) is a neuropeptide hormone that suppresses Th1-mediated cellular immunity. We previously reported that VIP-knockout (VIP-KO) mice have enhanced cellular immune responses and increased survival following murine cytomegalovirus (mCMV) infection in C57BL/6 mice. In th...

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Detalles Bibliográficos
Autores principales: Li, Jian-Ming, Darlak, Kasia A., Southerland, Lauren, Hossain, Mohammad S., Jaye, David L., Josephson, Cassandra D., Rosenthal, Hilary, Waller, Edmund K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664580/
https://www.ncbi.nlm.nih.gov/pubmed/23723978
http://dx.doi.org/10.1371/journal.pone.0063381