Synergistic Inhibition of Survival, Proliferation, and Migration of U87 Cells with a Combination of LY341495 and Iressa

Glioblastomas exploit various molecular pathways to promote glutamate- dependent growth by activating the AMPA (2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid) receptor, the group II metabotropic glutamate receptor, mGluR, and the epidermal growth factor receptor, EGFR. We hypothesized...

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Detalles Bibliográficos
Autores principales: Yelskaya, Zarina, Carrillo, Vangie, Dubisz, Ewa, Gulzar, Hira, Morgan, Devon, Mahajan, Shahana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664620/
https://www.ncbi.nlm.nih.gov/pubmed/23724064
http://dx.doi.org/10.1371/journal.pone.0064588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664620/
https://www.ncbi.nlm.nih.gov/pubmed/23724064
http://dx.doi.org/10.1371/journal.pone.0064588

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