Cargando…
Synergistic Inhibition of Survival, Proliferation, and Migration of U87 Cells with a Combination of LY341495 and Iressa
Glioblastomas exploit various molecular pathways to promote glutamate- dependent growth by activating the AMPA (2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid) receptor, the group II metabotropic glutamate receptor, mGluR, and the epidermal growth factor receptor, EGFR. We hypothesized...
Autores principales: | Yelskaya, Zarina, Carrillo, Vangie, Dubisz, Ewa, Gulzar, Hira, Morgan, Devon, Mahajan, Shahana S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664620/ https://www.ncbi.nlm.nih.gov/pubmed/23724064 http://dx.doi.org/10.1371/journal.pone.0064588 |
Ejemplares similares
-
AMPA receptor-mTORC1 signaling activation is required for neuroplastic effects of LY341495 in rat hippocampal neurons
por: Seo, Mi kyoung, et al.
Publicado: (2020) -
Effects of Chronic LY341495 on Hippocampal mTORC1 Signaling in Mice with Chronic Unpredictable Stress-Induced Depression
por: Seo, Mi Kyoung, et al.
Publicado: (2022) -
Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats
por: Podkowa, Karolina, et al.
Publicado: (2016) -
Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole
por: Liao, Sally, et al.
Publicado: (2017) -
Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma
por: Gemmill, R M, et al.
Publicado: (2005)