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Ectopic γ-catenin Expression Partially Mimics the Effects of Stabilized β-catenin on Embryonic Stem Cell Differentiation

β-catenin, an adherens junction component and key Wnt pathway effector, regulates numerous developmental processes and supports embryonic stem cell (ESC) pluripotency in specific contexts. The β-catenin homologue γ-catenin (also known as Plakoglobin) is a constituent of desmosomes and adherens junct...

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Detalles Bibliográficos
Autores principales: Mahendram, Sujeivan, Kelly, Kevin F., Paez-Parent, Sabrina, Mahmood, Sharmeen, Polena, Enio, Cooney, Austin J., Doble, Bradley W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664634/
https://www.ncbi.nlm.nih.gov/pubmed/23724138
http://dx.doi.org/10.1371/journal.pone.0065320