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A Peptide against Soluble Guanylyl Cyclase α1: A New Approach to Treating Prostate Cancer
Among the many identified androgen-regulated genes, sGCα1 (soluble guanylyl cyclase α1) appears to play a pivotal role in mediating the pro-cancer effects of androgens and androgen receptor. The classical role for sGCα1 is to heterodimerize with the sGCβ1 subunit, forming sGC, the enzyme that mediat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664642/ https://www.ncbi.nlm.nih.gov/pubmed/23724033 http://dx.doi.org/10.1371/journal.pone.0064189 |