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A Peptide against Soluble Guanylyl Cyclase α1: A New Approach to Treating Prostate Cancer

Among the many identified androgen-regulated genes, sGCα1 (soluble guanylyl cyclase α1) appears to play a pivotal role in mediating the pro-cancer effects of androgens and androgen receptor. The classical role for sGCα1 is to heterodimerize with the sGCβ1 subunit, forming sGC, the enzyme that mediat...

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Detalles Bibliográficos
Autores principales: Gao, Shuai, Hsieh, Chen-Lin, Bhansali, Meenakshi, Kannan, Archana, Shemshedini, Lirim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664642/
https://www.ncbi.nlm.nih.gov/pubmed/23724033
http://dx.doi.org/10.1371/journal.pone.0064189