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External pH modulates EAG superfamily K(+) channels through EAG-specific acidic residues in the voltage sensor
The Ether-a-go-go (EAG) superfamily of voltage-gated K(+) channels consists of three functionally distinct gene families (Eag, Elk, and Erg) encoding a diverse set of low-threshold K(+) currents that regulate excitability in neurons and muscle. Previous studies indicate that external acidification i...
Autores principales: | Kazmierczak, Marcin, Zhang, Xiaofei, Chen, Bihan, Mulkey, Daniel K., Shi, Yingtang, Wagner, Paul G., Pivaroff-Ward, Kendra, Sassic, Jessica K., Bayliss, Douglas A., Jegla, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664700/ https://www.ncbi.nlm.nih.gov/pubmed/23712551 http://dx.doi.org/10.1085/jgp.201210938 |
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