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Formation and dissociation of proteasome storage granules are regulated by cytosolic pH

The 26S proteasome is the major protein degradation machinery of the cell and is regulated at many levels. One mode of regulation involves accumulation of proteasomes in proteasome storage granules (PSGs) upon glucose depletion. Using a systematic robotic screening approach in yeast, we identify tra...

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Detalles Bibliográficos
Autores principales: Peters, Lee Zeev, Hazan, Rotem, Breker, Michal, Schuldiner, Maya, Ben-Aroya, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664706/
https://www.ncbi.nlm.nih.gov/pubmed/23690178
http://dx.doi.org/10.1083/jcb.201211146