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Cryo–electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering

Synaptic vesicles are embedded in a complex filamentous network at the presynaptic terminal. Before fusion, vesicles are linked to the active zone (AZ) by short filaments (tethers). The identity of the molecules that form and regulate tethers remains unknown, but Rab3-interacting molecule (RIM) is a...

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Detalles Bibliográficos
Autores principales: Fernández-Busnadiego, Rubén, Asano, Shoh, Oprisoreanu, Ana-Maria, Sakata, Eri, Doengi, Michael, Kochovski, Zdravko, Zürner, Magdalena, Stein, Valentin, Schoch, Susanne, Baumeister, Wolfgang, Lučić, Vladan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664715/
https://www.ncbi.nlm.nih.gov/pubmed/23712261
http://dx.doi.org/10.1083/jcb.201206063