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Cryo–electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering
Synaptic vesicles are embedded in a complex filamentous network at the presynaptic terminal. Before fusion, vesicles are linked to the active zone (AZ) by short filaments (tethers). The identity of the molecules that form and regulate tethers remains unknown, but Rab3-interacting molecule (RIM) is a...
Autores principales: | Fernández-Busnadiego, Rubén, Asano, Shoh, Oprisoreanu, Ana-Maria, Sakata, Eri, Doengi, Michael, Kochovski, Zdravko, Zürner, Magdalena, Stein, Valentin, Schoch, Susanne, Baumeister, Wolfgang, Lučić, Vladan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664715/ https://www.ncbi.nlm.nih.gov/pubmed/23712261 http://dx.doi.org/10.1083/jcb.201206063 |
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