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Effect of EME1 exon variant Ile350Thr on risk and early onset of breast cancer in southern Chinese women

Essential meiotic endonuclease 1 homolog 1 (EME1) is a key DNA repair protein that participates in the recognition and repair of DNA double-strand breaks. Deficiency of the EME1 gene can lead to spontaneous genomic instability and thus contribute to tumorgenesis. We hypothesized that the exon varian...

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Detalles Bibliográficos
Autores principales: Zhao, Jianwei, Liu, Lin, Zhang, Anqing, Chen, Qin, Fang, Wenxiang, Zeng, Lizhi, Lu, Jiachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664725/
https://www.ncbi.nlm.nih.gov/pubmed/23720674
http://dx.doi.org/10.7555/JBR.27.20130013