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Pharmacokinetics, Tolerability, and Safety of Intranasal Administration of Reformulated OxyContin(®) Tablets Compared with Original OxyContin(®) Tablets in Healthy Adults

BACKGROUND AND OBJECTIVE: Reformulated OxyContin(®) (oxycodone-HCl controlled release) tablets (ORF) became available in the United States in August 2010. The original formulation of OxyContin(®) (oxycodone-HCl controlled release) tablets (OC) used a delivery system that did not provide inherent res...

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Detalles Bibliográficos
Autores principales: Perrino, Peter J., Colucci, Salvatore V., Apseloff, Glen, Harris, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664752/
https://www.ncbi.nlm.nih.gov/pubmed/23677743
http://dx.doi.org/10.1007/s40261-013-0085-x