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Fluorescence monitoring of riboswitch transcription regulation using a dual molecular beacon assay
Riboswitches are mRNA elements that specifically bind cellular metabolites and control gene expression by modifying their structure. As riboswitches often control essential genes in pathogenic bacteria, riboswitches have been proposed as new targets for antibiotics. High-throughput screening provide...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664795/ https://www.ncbi.nlm.nih.gov/pubmed/23525464 http://dx.doi.org/10.1093/nar/gkt190 |