Zebrafish AID is capable of deaminating methylated deoxycytidines

Activation-induced cytidine deaminase (AID) deaminates deoxycytidine (dC) to deoxyuracil (dU) at immunoglobulin loci in B lymphocytes to mediate secondary antibody diversification. Recently, AID has been proposed to also mediate epigenetic reprogramming by demethylating methylated cytidines (mC) pos...

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Detalles Bibliográficos
Autores principales: Abdouni, Hala, King, Justin J., Suliman, Mussa, Quinlan, Matthew, Fifield, Heather, Larijani, Mani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664802/
https://www.ncbi.nlm.nih.gov/pubmed/23585279
http://dx.doi.org/10.1093/nar/gkt212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664802/
https://www.ncbi.nlm.nih.gov/pubmed/23585279
http://dx.doi.org/10.1093/nar/gkt212

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