OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds

A crucial step in analyzing mRNA-Seq data is to accurately and efficiently map hundreds of millions of reads to the reference genome and exon junctions. Here we present OLego, an algorithm specifically designed for de novo mapping of spliced mRNA-Seq reads. OLego adopts a multiple-seed-and-extend sc...

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Detalles Bibliográficos
Autores principales: Wu, Jie, Anczuków, Olga, Krainer, Adrian R., Zhang, Michael Q., Zhang, Chaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664805/
https://www.ncbi.nlm.nih.gov/pubmed/23571760
http://dx.doi.org/10.1093/nar/gkt216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664805/
https://www.ncbi.nlm.nih.gov/pubmed/23571760
http://dx.doi.org/10.1093/nar/gkt216

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