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Quantitative in vivo analysis of chromatin binding of Polycomb and Trithorax group proteins reveals retention of ASH1 on mitotic chromatin

The Polycomb (PcG) and Trithorax (TrxG) group proteins work antagonistically on several hundred developmentally important target genes, giving stable mitotic memory, but also allowing flexibility of gene expression states. How this is achieved in quantitative terms is poorly understood. Here, we pre...

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Detalles Bibliográficos
Autores principales: Steffen, Philipp A., Fonseca, João Pedro, Gänger, Cornelia, Dworschak, Eva, Kockmann, Tobias, Beisel, Christian, Ringrose, Leonie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664806/
https://www.ncbi.nlm.nih.gov/pubmed/23580551
http://dx.doi.org/10.1093/nar/gkt217