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Dissecting the roles of the histone chaperones reveals the evolutionary conserved mechanism of transcription-coupled deposition of H3.3

The mammalian genome encodes multiple variants of histone H3 including H3.1/H3.2 and H3.3. In contrast to H3.1/H3.2, H3.3 is enriched in the actively transcribed euchromatin and the telomeric heterochromatins. However, the mechanism for H3.3 to incorporate into the different domains of chromatin is...

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Detalles Bibliográficos
Autores principales: Song, Yunkyoung, Seol, Ja-Hwan, Yang, Jae-Hyun, Kim, Hye-Jin, Han, Jeung-Whan, Youn, Hong-Duk, Cho, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664809/
https://www.ncbi.nlm.nih.gov/pubmed/23563152
http://dx.doi.org/10.1093/nar/gkt220