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Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1
Transcription-blocking oxidative DNA damage is believed to contribute to aging and to underlie activation of oxidative stress responses and down-regulation of insulin-like signaling (ILS) in Nucleotide Excision Repair (NER) deficient mice. Here, we present the first quantitative proteomic descriptio...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664812/ https://www.ncbi.nlm.nih.gov/pubmed/23580547 http://dx.doi.org/10.1093/nar/gkt225 |