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Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1

Transcription-blocking oxidative DNA damage is believed to contribute to aging and to underlie activation of oxidative stress responses and down-regulation of insulin-like signaling (ILS) in Nucleotide Excision Repair (NER) deficient mice. Here, we present the first quantitative proteomic descriptio...

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Detalles Bibliográficos
Autores principales: Arczewska, Katarzyna D., Tomazella, Gisele G., Lindvall, Jessica M., Kassahun, Henok, Maglioni, Silvia, Torgovnick, Alessandro, Henriksson, Johan, Matilainen, Olli, Marquis, Bryce J., Nelson, Bryant C., Jaruga, Pawel, Babaie, Eshrat, Holmberg, Carina I., Bürglin, Thomas R., Ventura, Natascia, Thiede, Bernd, Nilsen, Hilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664812/
https://www.ncbi.nlm.nih.gov/pubmed/23580547
http://dx.doi.org/10.1093/nar/gkt225