Cargando…

Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage

Telomere integrity is critical for telomere function and genomic stability. We previously demonstrated that non-erythroid α-spectrin (αIISp) is present in mammalian cell nuclei where it is important in repair of DNA interstrand cross-links (ICLs) and chromosome stability. We now demonstrate that αII...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Pan, Herbig, Utz, Coffman, Frederick, Lambert, Muriel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664817/
https://www.ncbi.nlm.nih.gov/pubmed/23571757
http://dx.doi.org/10.1093/nar/gkt235