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Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage
Telomere integrity is critical for telomere function and genomic stability. We previously demonstrated that non-erythroid α-spectrin (αIISp) is present in mammalian cell nuclei where it is important in repair of DNA interstrand cross-links (ICLs) and chromosome stability. We now demonstrate that αII...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664817/ https://www.ncbi.nlm.nih.gov/pubmed/23571757 http://dx.doi.org/10.1093/nar/gkt235 |