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Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos

Adenosine deaminases-acting-on-RNA (ADAR) proteins induce adenosine-to-inosine editing in double-stranded RNA molecules. This editing generates RNA diversity at the post-transcriptional level, and it has been implicated in the control of cell differentiation and development. The editing of microRNA...

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Detalles Bibliográficos
Autores principales: García-López, Jesús, Hourcade, Juan de Dios, del Mazo, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664825/
https://www.ncbi.nlm.nih.gov/pubmed/23571754
http://dx.doi.org/10.1093/nar/gkt247