Cargando…

Loop-miRs: active microRNAs generated from single-stranded loop regions

MicroRNAs (miRNAs) are key mediators of post-transcriptional gene regulation. The miRNA precursors are processed by the endonucleases Drosha and Dicer into a duplex, bound to an Argonaute protein and unwound into two single-stranded miRNAs. Although alternative ways to generate miRNAs have been disc...

Descripción completa

Detalles Bibliográficos
Autores principales: Winter, Julia, Link, Steffen, Witzigmann, Dominik, Hildenbrand, Catherina, Previti, Christopher, Diederichs, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664828/
https://www.ncbi.nlm.nih.gov/pubmed/23580554
http://dx.doi.org/10.1093/nar/gkt251