The Yin and Yang of tRNA: proper binding of acceptor end determines the catalytic balance of editing and aminoacylation

Faithful translation of the genetic code depends on accurate coupling of amino acids with cognate transfer RNAs (tRNAs) catalyzed by aminoacyl-tRNA synthetases. The fidelity of leucyl-tRNA synthetase (LeuRS) depends mainly on proofreading at the pre- and post-transfer levels. During the catalytic cy...

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Detalles Bibliográficos
Autores principales: Tan, Min, Wang, Meng, Zhou, Xiao-Long, Yan, Wei, Eriani, Gilbert, Wang, En-Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664829/
https://www.ncbi.nlm.nih.gov/pubmed/23585282
http://dx.doi.org/10.1093/nar/gkt252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664829/
https://www.ncbi.nlm.nih.gov/pubmed/23585282
http://dx.doi.org/10.1093/nar/gkt252

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